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Circulating microbial DNA: a novel pancreatic tumor marker and prognostic indicator

Circulating microbial DNA: a novel pancreatic tumor marker and prognostic indicator

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096767
Enrollment
Unknown
Registered
2025-02-06
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

Gold Standard:The pathological diagnosis was pancreatic cancer
Index test:Circulating microbial DNA

Sponsors

Zhongshan Hospital Affiliated to Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age over 18 years old, gender is not limited; ECOGPS score: 0~ 2 points; 2. Possible pancreatic lesions suggested by ultrasound, CT, MRI and other imaging or clinical examinations, with clinical symptoms related to pancreatic cancer, such as abdominal pain, indigestion, weight loss, etc. or cases confirmed by pathological examination as pancreatic cancer. 3. Sign the informed consent form and be able to comply with the requirements of the program; 3.if the patient cannot sign the informed consent form, the legal guardian or agent must sign it.

Exclusion criteria

Exclusion criteria: 1. Past or concurrent with other malignant tumors; 2. Patients with serious diseases of important organs such as heart, lung, kidney, brain, blood, etc. 3. Patients with severe neurological and psychiatric diseases (such as epilepsy, depression, mania, seizures, schizophrenia, etc.); 4. Pregnant or lactating women or patients who have pregnancy plans during the study and are unwilling to use contraception; 5. The researcher believes that the subject's current condition is not suitable for participating in this study; 6. Patients who participate in other clinical research trials at the same time.

Design outcomes

Secondary

MeasureTime frame
Time to live;

Primary

MeasureTime frame
cmDNA;sensitivity;specificity;Positive predictive value;Negative predictive value;

Countries

China

Contacts

Public ContactYongjie Su

Zhongshan Hospital Affiliated to Xiamen University

syj_xm@163.com+86 592 2993142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026