Acute organophosphorus pesticide poisoning
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >=18 years; 2.Patients who have taken organophosphate pesticides orally in our hospital and received standard treatment within 6 hours; 3.Patients with confirmed serum cholinesterase activity and a definitive clinical diagnosis were included;
Exclusion criteria
Exclusion criteria: 1.Patients without oral organophosphate poisoning; 2.Patients who were referred to our hospital from other hospitals had a time of more than 6 hours from the time of taking pesticides to the time of admission; 3.Patients with severe chronic comorbidities, including cirrhosis, symptomatic heart failure;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular ejection fraction (LVEF);Ventricular wall motion;Changes in the structure of the myocardium;Troponin I, pro-brain natriuretic peptide;Serum myocardial enzymes: aspartate aminotransferase, lactate dehydrogenase, a-hydroxybutyrate dehydrogenase, creatine kinase; | — |
Secondary
| Measure | Time frame |
|---|---|
| Continuous ECG and pulse oxygen saturation monitoring; | — |
Countries
China
Contacts
Huzhou Center Hospital