Attention Deficit Hyperactivity Disorder (ADHD)
Conditions
Interventions
real rTMS-tDCS group:rTMS treatment was conducted using the Magneuro100 magnetic stimulator (VCB001 model, Nanjing Weis Medical Technology Co., Ltd.), equipped with an "8" shaped coil. The rTMS treat
B. Localization: The coil was placed over the cortical representation area of the left abductor pollicis brevis, where the resting motor threshold (RMT) was measured, and then moved 5 cm forward to th
C. Stimulus Frequency: 10 Hz
D. Stimulus Intensity: 100% of resting motor threshold (RMT)
E. Stimulus Duration: 4 seconds, with a 26-second interval
F. Treatment Duration: Each session lasted 30 minutes, with 2400 pulses per session.
For tDCS stimulation, a high-precision transcranial direct current stimulator (Nanjing Wogao Medical Technology Co.
B. Stimulus Duration: 20 minutes
C. Stimulus Target: Right dorsolateral prefrontal cortex (r-DLPFC)
D. Polarity: Anode
E. Localization: Localization was performed using a 10-10 EEG cap designed for transcranial direct current stimulation, with the central anode placed at F4 and the remaining electrodes placed around i
real rTMS group:The group receiving only rTMS treatment had the same parameters as the real rTMS-tDCS group.
real tDCS group:The group receiving only tDCS treatment had the same parameters as the real rTMS-tDCS group.
sham group:For the sham rTMS treatment, a sham coil specifically designed for the ma
Sponsors
West China Second University Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1.Aged 5-12 years; 2. Meet the diagnostic criteria for ADHD as outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) by the American Psychiatric Association; 3.IQ >= 80 as measured by the Wechsler Intelligence Scale for Children (WISC); 4. Have not received non-invasive brain stimulation therapy previously.
Exclusion criteria
Exclusion criteria: 1.A history of seizures (including febrile seizures); 2.Taking benzodiazepines (equivalent to lorazepam >=2mg) or anticonvulsants; 3.A history of major medical or neurological diseases; 4.Idiopathic ASD(such as fragile x syndrome, tuberous sclerosis); 5.History of severe head injury; 6.There are metal implants in the skull; 7.Generalized developmental disorder (PDD) patients, because the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) criteria specify PDD as an excluded diagnosis of attention deficit hyperactivity disorder; 8.Patients with an IQ of less than 70 (based on the Wechsler Intelligence Scale for Children) were excluded from the study; 9.Children with mental illness or serious illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional near - infrared spectroscopy (fNIRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Behavior Rating Inventory of Executive Function, Second Edition (BRIEF-2) ;Conners' Rating Scales (CRS) score;IVA-CPT (Integrated Visual and Auditory Continuous Performance Test) ;Child Behavior Checklist (CBCL) score; | — |
Countries
china
Contacts
Public ContactHui zhou
Department of Rehabilitation, West China Second University Hospital, Sichuan University
Outcome results
None listed