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Perioperative dexmedetomidine improves sleep quality in gynecologic patients

A prospective study of the effect of dexmedetomidine on perioperative sleep quality in gynecologic surgery patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096752
Enrollment
Unknown
Registered
2025-02-06
Start date
2025-03-01
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep disorder

Interventions

MD Group (Composite Dextromet Group):Dextromet low-dose nasal spray was given on the evening before surgery and the evening after surgery, and intraoperative dextromet was pumped intravenously to prev
SD Group (Single Species Right American Group): intraoperative dextromet was pumped intravenously to prevent sleep disorders only
Group C (Control group):Administer physiological saline solution

Sponsors

Maternal and Child Health Hospital of Linping District, Hangzhou
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 18-60 years, American Society of Anesthesiologists (ASA) class I-III, no history of psychiatric illness, no other medical studies.

Exclusion criteria

Exclusion criteria: (1) Preoperative Pittsburgh Sleep Quality Index (PSQI) >= 7 or Athens Insomnia Scale (AIS) >= 6; (2) Sleep apnea or moderate or severe snoring; (3) Implantation of an in situ pacemaker, preoperative sinus bradycardia (heart rate < 50 beats/min) or sinus node disease, second or third degree atrioventricular block; (4) Preoperative communication disorders; (5) Severe liver or renal insufficiency; (6) Preoperative anti-epileptic, antidepressant and other psychotropic drugs; (7) Serious surgery-related adverse reactions and complications during the perioperative period.

Design outcomes

Primary

MeasureTime frame
sleep quality;

Secondary

MeasureTime frame
Postoperative pain, nausea and vomiting;Pain score;Adverse reactions;

Countries

China

Contacts

Public ContactSufeng Lin

Linping District Women and Children Care Hospital, Hangzhou

jld15967106092@163.com+86 159 6710 6092

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026