Breast cancer
Conditions
Interventions
Selecting individuals with Triple-Negative Breast Cancer (TNBC) for immunotherapy, the group with effective immunotherapy as the case group, and the group with ineffective immunotherapy as the control
Sponsors
Guangzhou First People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Histopathologically confirmed triple-negative breast cancer (TNBC); 2. Underwent a treatment regimen combining immunotherapy and chemotherapy; 3. Possessed breast standard MRI images before treatment and at the end of the first, second, and sixth courses of therapy; 4. Complete pathological tissue sample data; 5. Comprehensive efficacy evaluation data available.
Exclusion criteria
Exclusion criteria: 1. Discontinuation of treatment due to severe adverse effects; 2. Lack of complete clinical data; 3. Underwent breast-related treatment before the initial MRI examination; 4. Incomplete MRI image data or poor image quality; 5. Insufficient pathological tissue samples for evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunotherapy Efficacy in Solid Tumors;Area Under the Curve,AUC;Sensitivity;Specificity;Accuracy; | — |
Countries
China
Contacts
Public ContactYuan Guo
Guangzhou First People's Hospital
Outcome results
None listed