Polycystic ovary syndrome (PCOS) is one of the most common reproductive endocrine diseases in women of childbearing age. The main characteristics of PCOS are follicular dysplasia, persistent anovulation, hypersteroidal hormone synthesis, polycystic ovary changes and insulin resistance with hyperinsulinemia.
Conditions
Interventions
experimental group (the diagnosis was polycystic ovary syndrome):None
control group (tubal factor or male factor):None
Sponsors
Quzhou People Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1.Meeting the Rotterdam clinical diagnostic criteria for polycystic ovary syndrome: 1. Abnormal menstruation such as oligovulatory or anovulatory. 2. Clinical manifestations of hyperandrogenemia and/or hyperandrogenemia. 3.PCOM: >=12 follicles 2-9 mm in diameter in one or both ovaries. Comply with 2 of the above.
Exclusion criteria
Exclusion criteria: 1. Those who have chronic diseases, smoke or drink alcohol; 2. Those who have taken sex hormones or drugs affecting lipid metabolism in the past 6 months; 3.Patients with other disorders that cause irregular menstrual cycles: 3. Primary hypothyroidism and Cushing's syndrome lead to secondary obesity and drug-induced obesity. 4. Patients with diabetes, hypertension, coronary heart disease and hyperlipidemia; 5. Patients with severe hepatic and renal dysfunction; 6. Patients with acute, chronic infections, autoimmune, hereditary and infectious diseases; 7. Patients with history of malignant tumor and mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), total testosterone (TT), dehydroepiandrosterone sulfate (DHEA-S)?height?body weight?reasons of infertility?outcome of ART;The number and activity of ILC2 cells; | — |
Countries
China
Contacts
Public ContactLicong XU
Quzhou People Hospital
Outcome results
None listed