Neonatal Hypoxic-Ischemic Encephalopathy (HIE)
Conditions
Interventions
Hypothermia Treatment Group:None
Non-Hypothermia Treatment Group:None
Control Group:None
Sponsors
The Seventh Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Children with HIE treated with hypothermia Inclusion Criteria: a. Diagnosed with HIE b. No more than 12 hours after birth c. Willing to sign the informed consent form and comply with the study protocol d. Neonates with gestational age > = 37 weeks e. There is no damage to the head and can move slightly f. Receiving hypothermia therapy 2. Children with HIE who have not received hypothermia treatment Inclusion Criteria: a. Diagnosed with HIE b. No more than 24 hours after birth c. Willing to sign the informed consent form and comply with the study protocol d. Neonates with gestational age > = 37 weeks e. There is no damage to the head and can move slightly 3. Children in the control group Inclusion Criteria: a. Children with jaundice b. Willing to sign informed consent and comply with the study protocol c. Neonates with gestational age > = 37 weeks
Exclusion criteria
Exclusion criteria: 1. Children with HIE treated with hypothermia Exclusion Criteria: a. Not diagnosed with HIE b. More than 24 hours after birth c. Have congenital diseases, such as heart disease, chromosomal malformations, hereditary metabolic abnormalities d. Neonates with a gestational age of < 37 weeks 2. Children with HIE who have not received hypothermia treatment Exclusion Criteria: a. Not diagnosed with HIE b. Have congenital diseases, such as heart disease, chromosomal malformations, hereditary metabolic abnormalities c. Neonates with a gestational age of <37 weeks 3. Children in the control group Exclusion Criteria: a. Have congenital diseases, such as heart disease, chromosomal malformations, hereditary metabolic abnormalities b. Newborns with a gestational age of <37 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood flow;Blood flow velocity;Vascular cross-sectional area;Hemoglobin concentration;Weight;Head circumference;Height;Electrophysiologic features and abnormal nerve conduction patterns;Craniocerebral vascular morphology and hemoglobin distribution; | — |
Countries
China
Contacts
Public ContactZhichun Feng
The Seventh Medical Center of Chinese PLA General Hospital
Outcome results
None listed