Deep venous thrombosis of lower extremity in patients with severe neurological coma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1?age >=18 years old, gender unlimited, new to the NICU basically no active limb movement patients; 2? 5<=GCS<=9 score and ultrasound examination excluded patients who had been resuscitation after surgery or who did not need surgery within 2 weeks; 3? Patients who are expected to remain hospitalized in NICU within 2 weeks; 4?the lower limbs are sound, no structural abnormalities caused by amputation or other reasons or other factors affecting joint activity; 5?Patients whose legal representatives voluntarily agree to participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Those who meet one of the following conditions are not eligible for inclusion:1?Patients with severe disease and unstable hemodynamics; 2? lower extremity limb deformity or joint structural disease affect passive activity; 3?Patients admitted to hospital have been clearly diagnosed with severe coagulation dysfunction or even diagnosed with DVT; 4?Participants in any other clinical trial within 1 month before baseline; 5?The researcher believes that it is inappropriate to participate in this study; 6?Patients who received anticoagulation or antiplate therapy within 1 week before and after enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower extremity venous thrombosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of thrombotic vein branches formed within 2 weeks;Change rate of D-Dimer within 2 weeks;Creatine kinase change rate over 2 weeks; | — |
Countries
China
Contacts
Xuanwu Hospital Capital Medical University