Acute myocardial infarction
Conditions
Interventions
Female patient group:SGLT2 inhibitors
Male patient group:SGLT2 inhibitors
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.18-80 years old; 2. Acute myocardial infarction (including acute ST-segment elevation myocardial infarction and acute non-ST-segment elevation myocardial infarction); 3. No previous use of an SGLT2 inhibitor; 4. Adding an SGLT2 inhibitor for diabetes or heart failure.
Exclusion criteria
Exclusion criteria: 1.Previous or current use of SGLT2 inhibitors; 2.Renal insufficiency (glomerular filtration rate < 30 mL/min/1.73 m2); 3.Pregnancy, lactation, history of cancer within the past 3 years, autoinflammatory disease, current or planned long-term systemic glucocorticoid therapy, acute symptomatic urinary tract infection or genital infection, clinically significant nontransient hematologic disease: contraindications to SGLT2 inhibitors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proBNP;Left ventricular ejection fraction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Other echocardiographic indicators;Laboratory tests: included cardiac troponin, blood lipids, fasting blood glucose, glycated hemoglobin, serum creatinine, urea nitrogen, and glomerular filtration rate;The clinical endpoints: all-cause death, cardiovascular death, rehospitalization (cardiovascular and other causes), recurrent myocardial infarction and stroke;Length of hospital stay;Total cost of hospitalization; | — |
Countries
China
Contacts
Public ContactChen Guo
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed