Sepsis
Conditions
Interventions
Sepsis group:None
control group:None
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients who undergo tracheal intubation within the ICU or are intubated within 24 hours after intubation, have no evidence of pneumonia before admission (i.e. no new or ongoing complications), and have an estimated intubation time of>96 hours, aged 18-90 years, are divided into sepsis group and non sepsis group based on whether they meet the diagnostic criteria for sepsis (infection+SOFA score>2 points).
Exclusion criteria
Exclusion criteria: Expected to take less than 96 hours of tubing; Under 18 years old; Pregnancy or lactation period; Expected circulatory respiratory failure requiring rescue; Evaluate patients who cannot tolerate sputum suction; Patients with lung injury caused by aspiration, chest trauma, or other reasons before the start of mechanical ventilation; Patients who continuously take antibiotics before mechanical ventilation; Individuals with a history of chronic pulmonary infections; Long term consumption of probiotic products; Patients with acute or chronic respiratory infections, mutations, trauma, and other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Airway microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| oxygenation index;blood gas analysis; | — |
Countries
China
Contacts
Public ContactKeliang Xie
Tianjin Medical University General Hospital
Outcome results
None listed