None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Aged between 18 and 70 years. (2) Patients with Helicobacter pylori eradication failure, guided by antibiotic susceptibility testing. (3) Positive result in the ^13C urea breath test. (4) Voluntarily participating in this clinical trial, providing informed consent, and signing the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Received H. pylori treatment or related therapies in the past four weeks. (2) Taken any of the following medications within one month prior to specimen collection: antibiotics, probiotics, acid-suppressive drugs, or antimicrobial traditional Chinese medicine. (3) Taking anticoagulant medications and unable to undergo gastric mucosal biopsy. (4) Suffering from severe primary conditions such as heart, liver, kidney, lung, hematologic, or neurological diseases. (5) Unable to tolerate painless gastroscopy. (6) Pregnant or breastfeeding women. (7) Patients deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori Genome; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University