Degenerative lumbar disease
Conditions
Interventions
Group A:Augmentation of the L5 superior endplate
Group B:Bilateral endplate augmentation of L4-5
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: (1) L4-5 lumbar spinal stenosis with degenerative instability, or L4-5 degenerative spondylolisthesis, with persistent symptoms despite at least three months of conservative treatment; (2) Elderly patients aged >60 years; (3) Imaging indicating osteoporosis, or quantitative CT of the vertebral body showing bone mineral density <80 mg/cm³.
Exclusion criteria
Exclusion criteria: (1) Patients with lumbar degenerative spondylolisthesis graded Meyerding II or higher; (2) Patients with imaging findings showing varying degrees and ranges of endplate sclerosis; (3) Patients with a history of spinal tumors, tuberculosis, or previous spinal surgeries; (4) Patients with severe acute or chronic infections; (5) Patients with severe chronic diseases, such as heart disease or renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cage subsidence status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fusion status;Visual analogue score;Oswestry Disability Index ; | — |
Countries
China
Contacts
Public ContactTianhang Xie
West China Hospital of Sichuan University
Outcome results
None listed