prediabetes
Conditions
Interventions
Intervention Group 1:The energy distribution in the morning, noon and evening is 3:5:2, and the energy supply ratio of fat throughout the day is 35% (the energy supply ratio of carbohydrates is 45%, a
Intervention Group 2:The energy distribution in the morning, noon and evening is 3:5:2, and the energy supply ratio of fat throughout the day is 25% (the energy supply ratio of carbohydrates is 55%, a
Intervention Group 3:The energy distribution in the morning, noon and evening is 5:3:2, and the energy supply ratio of fat throughout the day is 35% (the energy supply ratio of carbohydrates is 45%, a
Intervention Group 4:The energy distribution in the morning, noon and evening is 5:3:2, and the energy supply ratio of fat throughout the day is 25% (the energy supply ratio of carbohydrates is 55%, a
Sponsors
Shanghai University of Medicine & Health Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. People with prediabetes; 2. Aged 30-75 years old, with stable weight for nearly 6 months (+/-2kg); 3. Stable medication for nearly 3 months; 4. BMI >= 24 or male waist circumference >= 90cm/ female waist circumference >= 85cm.
Exclusion criteria
Exclusion criteria: 1. Myocardial infarction or stroke in the past 6 months; 2. Liver and kidney damage and concurrent medication use; 3. Diabetes or long-term use of medications that affect blood sugar control (such as systemic glucocorticoids, steroids, thiazide diuretics); 4. Disease conditions that affect energy metabolism or glucose metabolism (Cushing's syndrome, chronic kidney disease, acromegaly, cirrhosis, inflammatory bowel disease, cardiomyopathy, chronic obstructive pulmonary disease); 5. Cancer in the past 2 years; 6. Mental illness, hearing and visual impairment, and limb disability.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OGTT blood glucose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Basic information such as gender, age, lifestyle, disease and medication history;Physical examination including height, weight, waist circumference, blood pressure, body composition, etc.;Complete blood test;Fecal microbial testing;Urine metabolomics;Blood lipids, liver function, kidney function, serum oxidative inflammation and other indicators; | — |
Countries
China
Contacts
Public ContactLixin Na
Shanghai University of Medicine & Health Sciences
Outcome results
None listed