Propofol-induced injection pain
Conditions
Interventions
Esketamine group:Esketamine injection was intravenously injected, and 45 seconds later, propofol was intravenously injected.
Lidocaine group:Mixture of propofol and lidocaine was injected intravenously 45 seconds after the same volume of normal saline was injected intravenously.
Sponsors
Anhui Children's Hospital
Eligibility
Sex/Gender
All
Age
2 Years to 10 Years
Inclusion criteria
Inclusion criteria: 1.Children undergoing elective short operation (< one hour), aged 2-10 years; 2.ASA grade ? or ?; 3.Guardians agree to sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Allergy to anesthetic drugs; 2. Combined with cardiovascular, hepatic, renal or psychiatric diseases, history of seizures or intracranial hypertension; 3. The history of upper respiratory tract infection within the last 1 weeks; 4. Obesity (BMI>=95% for age and sex); 5. Crying when you enter the house.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Propofol injection pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics;Emergence agitation score, PAED;Adverse reactions; | — |
Countries
China
Contacts
Public ContactLi Chen
Anhui Children's Hospital
Outcome results
None listed