Late-life depression
Conditions
Interventions
Mindfulness-based cognitive therapy group:The Mindfulness-Based Cognitive Therapy (MBCT) group will undergo a 4-week intervention, using a combined online and offline mindfulness treatment program. Th
Health education group:The Health Education group will undergo a 4-week intervention, consisting of 8 themed health education sessions. The courses cover common diseases and health care knowledge in t
Coronary Heart Disease
Diabetes Mellitus
Hypertension
Cerebrovascular Disease
Osteoarthritis
Deme
Sponsors
Peking University Sixth Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: a. Age>= 60 years, gender unrestricted. b. Patients with a past or current diagnosis of unipolar depression (single or recurrent episodes) according to the ICD-10 criteria, confirmed by two attending physicians. c. A score of >= 14 on the 24-item Hamilton Depression Rating Scale (HDRS), with stable pharmacological treatment for at least two weeks. d. Patients are able to understand and cooperate with the treatment. e. Informed consent form has been signed.
Exclusion criteria
Exclusion criteria: a. Patients with severe suicidal risk. b. Patients with a Mini-Mental State Examination (MMSE) score of less than 24. c. Patients who meet the diagnostic criteria for any other mental disorder in the ICD-10, in addition to depression. d. Patients with severe somatic diseases resulting in impaired function of vital organs, or who cannot complete the treatment requirements due to other somatic diseases. e. Patients who are simultaneously receiving other forms of psychotherapy or participating in other therapeutic studies. f. Patients using central nervous system stimulants, antipsychotics, anti-dementia medications, or anti-Parkinson’s drugs concurrently. g. Patients who have received electroconvulsive therapy (ECT) with or without convulsions, transcranial magnetic stimulation (TMS), or deep brain stimulation (DBS) within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression severity score;Anxiety severity score;Screening for psychological and mental health;Assessment of sleep quality;Assessment of overall life satisfaction;Assessment of health-related quality of life;Cognitive function score;Neural activity and functional state of the brain;Electroencephalographic activity;Cardiac function;Pulmonary function;The composition of blood cells and basic functional status;Immune indicators; | — |
Countries
China
Contacts
Public ContactSun Xinyu
Peking University Sixth Hospital
Outcome results
None listed