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Pathogenesis and prognostic value of liquefied necrotic lesions in the metastatic neck nodes of head and neck carcinoma

Pathogenesis and prognostic value of liquefied necrotic lesions in the metastatic neck nodes of head and neck carcinoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096682
Enrollment
Unknown
Registered
2025-02-04
Start date
2025-02-04
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck squamous cell carcinoma

Interventions

Group with necrotic metastatic neck nodes:NA

Sponsors

Eye & ENT Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1) The patient has signed the informed consent form and voluntarily joined this study; (2) Pathological diagnosis of head and neck squamous cell carcinoma; (3) Age: >= 18 years old. (4) Gender is not limited to men or women. (5) Liver and kidney function and blood routine are basically normal, including: liver function: serum alanine aminotransferase and alanine aminotransferase 60 ml/(min * 1.73m^2). Blood cells: neutrophil count >= 1.5 * 10^9, platelet count >= 100 * 10^9, hemoglobin >= 90g/l. (6) Imaging confirms the presence of lymph node metastasis. (7) Primary lesion staging is not limited (8) Expected good compliance.

Exclusion criteria

Exclusion criteria: (1) Currently participating in other clinical studies, and for participants who have previously participated in drug clinical trials, the interval from the last medication should be more than one month. (2) Patients with serious organ system diseases such as cardiovascular, digestive, urinary, and nervous system disorders, or severe acute and chronic medical conditions such as uncontrollable systemic infections, as well as mental illnesses (including recent [past year] or active suicidal ideation or behavior), who have been assessed by researchers as unsuitable for participation in this clinical study. (3) Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
sequencing analysis results;

Secondary

MeasureTime frame
clinical data;3-year disease-free survival time;3-year overall survival time;3-year cancer control rate;Tumor regression rate after induction chemotherapy;adverse reactions rate;

Countries

China

Contacts

Public ContactMing Zhang

Eye & ENT Hospital, Fudan University

zmzlm@163.com+86 21 6437 7134

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026