gastric tumors
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. age 18- 85 years (including threshold); 2. BMI: 18.5- 28 kg / m^2 (including threshold); 3. patients with gastric tumours scheduled for elective laparoscopic surgery under general anaesthesia.
Exclusion criteria
Exclusion criteria: 1. American Society of Anesthesiologists (ASA) Class >III; 2. Contraindications to regional anesthesia (coagulation abnormalities; patients with bacteremia, septicemia, or infection at the puncture site; patients with allergy to ropivacaine or lidocaine); 3. Pre-operative history of chronic pain; 4. Long-term use of opioids; 5. Cirrhosis of the liver or impaired renal function (estimated glomerular filtration rate <30 mL/min/1.73m^2); 6.unplanned intermediate open or postoperative ICU admission for continued mechanical ventilation; 7. patient noncooperation (defined as inability to clinically assess outcome metrics); 8. pregnancy or lactation; 9. participation in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| area under the curve of numeric rating scale for postoperative pain at rest between 0 to 24h (NRS, 0 ~ 10) ; | — |
Secondary
| Measure | Time frame |
|---|---|
| sensory block plane after 30 minutes of block;The mean arterial pressure, heart rate and SpO2 at five time points: (at rest, 10 minutes after induction, at skin incision, at skin suture, and at extubation);The dosage of propofol, remifentanil and sufentanil during the operation;The usage of the postoperative analgesic pump within 24 hours (the dosage of sufentanil within 24 hours, the time of the first PCIA, and the effective pressing times within 24 hours);NRS pain scores at rest and movement 1, 6, 12, and 24 hours after surgery;The time of the first postoperative relief analgesia, the number and dosage of the relief analgesia for 48h;Overall Benefit of analgesia Score (OBAS);quality of recovery at 24h after surgery (QoR-15);Postoperative recovery data, including first time to ventilate, first time to get out of bed, first time to eat (defined as oral liquid diet);Incidence of postoperative nausea and vomiting (PONV) (PONV);Length of stay (LOS); | — |
Countries
China
Contacts
The Affiliated Hospital of Xuzhou Medical University