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The Impact of Lobectomy and Segmentectomy on Pulmonary Vascular Resistance and Pulmonary Circulation, and Its Guiding Strategies for the Treatment of Pulmonary Arterial Hypertension

The Impact of Lobectomy and Segmentectomy on Pulmonary Vascular Resistance and Pulmonary Circulation, and Its Guiding Strategies for the Treatment of Pulmonary Arterial Hypertension

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096676
Enrollment
Unknown
Registered
2025-02-01
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Arterial Hypertension

Interventions

Left upper lobectomy group:none
Left upper lobe proper segmentectomy group:none

Sponsors

Ningbo Medical Centre Lihuili Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Previously underwent left upper lobectomy or left upper division segmentectomy. 2.All surgeries were performed using a completely thoracoscopic approach. 3.Preoperative examinations included echocardiography, chest CT, and pulmonary function tests conducted at our hospital. 4.Postoperative recovery was normal, with no severe infections, reoperations, or major complications, and lung re-expansion was satisfactory. 5.The patients were able to understand the study content, voluntarily signed informed consent forms, demonstrated good compliance, and cooperated in completing all required examinations. 6.age 0-18 years old.

Exclusion criteria

Exclusion criteria: 1.Having other diseases that affect pulmonary vascular resistance. 2.A history of chest trauma or thoracic surgery. 3.Patients with severe impairment of cardiac, hepatic, or renal function. 4.Patients with other malignant tumors or hematological diseases. 5.Pregnant, planning to become pregnant, and breastfeeding female patients. 6.Patients deemed unsuitable for enrollment by the investigators.

Design outcomes

Primary

MeasureTime frame
The angle between the left inferior pulmonary vein and the left atrium;

Secondary

MeasureTime frame
Pulmonary artery pressure;

Countries

China

Contacts

Public ContactDavis Zheng

Ningbo Medical Centre Lihuili Hospital

13429295441@163.com+86 13429295441

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026