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Evaluation study on the effectiveness and safety of Lubiprostone combined with magnesium sulfate in bowel preparation for elderly patients with constipation

Evaluation study on the effectiveness and safety of Lubiprostone combined with magnesium sulfate in bowel preparation for elderly patients with constipation

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096667
Enrollment
Unknown
Registered
2025-01-27
Start date
2024-09-24
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elderly constipation

Interventions

Experimental group:Lubiprostone
Control group:placebo

Sponsors

Shanghai Geriatric Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Patient aged 60 to 90 years; 2.The patient met the ROME IV diagnostic criteria for chronic constipation or the Bristol Stool Scale 1-2; 3.Able to understand and agree to participate in research;

Exclusion criteria

Exclusion criteria: 1.Bowle obstruction or perforation; 2.Acute gastrointestinal bleeding or the acute phase of inflammatory bowel disease; 3.Uncontrolled conditions such as congestive heart failure, unstable angina pectoris, unstable hypertension, arrhythmia, liver failure, acute kidney injury, uncontrolled blood sugar; 4.Allergy to the drugs used in this study; 5.Participated in other clinical trials within 3 months.

Design outcomes

Primary

MeasureTime frame
BBPS;—

Secondary

MeasureTime frame
fecal calprotectin levels;electrolyte changes;Patient satisfaction;Adenooma detection rate;—

Countries

China

Contacts

Public ContactLi Lei

Shanghai Geriatric Medical Center

li.lei@zs-hospital.sh.cn+86 13761481310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026