rebound pain
Conditions
Interventions
Esketamine(ES):Total volume of patient-controlled analgesia pump: 100ml (esketamine 1.25mg/kg + sufentanil 100ug + flurbiprofen axetil 100mg), background infusion rate: 2 ml/h, single dose: 2 ml, lock
Routine patient-controlled analgesia (PL):Total volume of patient-controlled analgesia pump: 100ml (e sufentanil 100ug + flurbiprofen axetil 100mg), background infusion rate: 2 ml/h, single dose: 2 ml
Sponsors
Ganzhou People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 75 who undergo unilateral shoulder arthroscopy surgery; 2. 18<= BMI <=30 kg/m^2; 3. ASA grades I-III; 4. Informed consent of the patient or her family members
Exclusion criteria
Exclusion criteria: 1. Contraindications to nerve block (preoperative nerve damage involving the surgical site, diabetes mellitus with peripheral neuropathy symptoms, bleeding or abnormal coagulation function, local or systemic infection); 2. Patients who take sedative and analgesic drugs or steroid drugs for a long time; 3. Patients with a history of neurological, psychiatric, or neuromuscular diseases; 4. Previous history of ipsilateral shoulder surgery; 5. Patients with a known allergy or contraindication to ropivacaine or esketamine and chronic analgesics; 6. Patients with a clear diagnosis of lung disease (chronic bronchitis, COPD, pulmonary bullae, pulmonary embolism, lung cancer, etc.); 7. Patients with severe cardiac disease (cardiac function grade III); 8. Hypertensive patients with poor blood pressure control (perioperative blood pressure: 180 / 100mmHg); 9. Patients who cannot complete the preoperative scale
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of rebound pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset, duration and intensity of rebound pain;time to the first analgesic request;Postoperative analgesic consumption;Rebound pain score;QoR-15 score;Adverse reactions;Quality of sleep;Pain scores at scheduled time points; | — |
Countries
China
Contacts
Public ContactLanhua Zhong
Ganzhou People's Hospital
Outcome results
None listed