Stroke
Conditions
Interventions
Experimental Group:Transcranial alternating current stimulation: Subjects are asked to sit in a comfortable recliner, turn off their smartphones, and are encouraged to drink water, relax, and fall asl
https://nexalin.com) Apply to the scalp: one electrode is placed on the forehead, the size of the electrode is 4.45×9.53cm, and the two electrodes are placed in the left and right mastoid areas respec
Control group:Sham stimulus: Subjects were asked to sit in a comfortable recliner, turn off their smartphones, and be encouraged to drink water, relax, and fall asleep. Three electrodes manufactured b
https://nexalin.com) Apply to the scalp: one electrode is placed on the forehead, the electrode is 4.45×9.53cm, the two electrodes are placed in the left and right mastoid areas respectively, the size
Sponsors
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Ischemic stroke confirmed by CT/MRI; 2. Aged >=30 years and =3 months and 8 points and <16 points; 6. Difficulty falling asleep/maintaining sleep/awakening too early at least 3 nights a week for more than 3 months.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to MRI, such as pacemakers, heart stents, claustrophobia, etc.; 2. Patients who have participated in or are currently participating in other clinical projects one month before enrollment; 3. Patients with contraindications to transcranial electrical stimulation, such as cochlear implants, history of epilepsy, and metal implants in the body; 4. Pregnant or lactating women; 5. Patients with severe mental illness, such as depression, schizophrenia, etc.; 6. Patients with sleep disorders caused by other reasons before stroke; 7. Patients with severe cognitive impairment and inability to understand or cooperate with the research process; 8. Patients with sleep disorders who have taken insomnia medication regularly for more than 3 months before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep response rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index score, PSQI;Amplitude of Low Frequency Fluctuation,ALFF;Regional Homogeneity,ReHo;Functional Connectivity,FC;EEG indicators;Hamilton anxiety scale score,HAMA;Hamilton depression scale score,HAMD; | — |
Countries
China
Contacts
Public ContactXue Xin
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed