Aneurysmal subarachnoid hemorrhage
Conditions
Interventions
Intervention group:Intermittent Lumbar Drainage
Control group:Continuous Lumbar Drainage
Sponsors
the Affiliated Hospital of Southwest Medical Univers
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1: Age >=18 and <=70 years. 2: Modified Rankin Scale (mRS) score <=1 before the current event. 3: Subarachnoid hemorrhage (SAH) due to ruptured intracranial aneurysm confirmed by computed tomography angiography (CTA) or digital subtraction angiography (DSA). 4: Underwent surgical treatment for the ruptured aneurysm. 5: Patient and/or legal guardian provided informed consent for LD treatment. 6: Patient and/or legal guardian agreed to long-term follow-up. 7: Patient and/or legal guardian provided written informed consent after fully reading and understanding the patient information sheet.
Exclusion criteria
Exclusion criteria: 1: Age 70 years. 2: Presence of unruptured intracranial aneurysms. 3: SAH due to traumatic or infectious aneurysm rupture. 4: History of hemorrhagic stroke. 5: History of hydrocephalus. 6: History of coagulopathy. 7: Presence of other severe intracranial diseases, including but not limited to: moyamoya disease, arteriovenous malformation (AVM), arteriovenous fistula (AVF), and malignant brain tumors. 8: Presence of other severe comorbidities, including but not limited to: severe depression, cancer (with a high likelihood of death within 2 years), and multi-organ failure. 9: Patient or legal guardian refused treatment. 10: Currently enrolled in other clinical trials with interventions that could interfere with the results of this study. 11: Any other condition deemed unsuitable for participation by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of other complications related to subarachnoid hemorrhage (mainly including: rerupture hemorrhage, fever, cerebral vasospasm, cerebral vasospasm related cerebral infarction, etc.);Incidence of shunt dependent hydrocephalus; | — |
Countries
China
Contacts
Public ContactJianhua Peng
Department of Neurosurgery, the Affiliated Hospital of Southwest Medical Univers
Outcome results
None listed