Postherpetic neuralgia
Conditions
Interventions
Esketamine group:Esketamine for intravenous controlled analgesia
Control group:Normal saline for intravenous controlled analgesia
Sponsors
Ningbo Medical Centre Lihuili Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The diagnosis of PHN was based on the Expert Consensus on the Diagnosis and Treatment of herpes zoster in China (2022); 2. Have a history of shingles, and the neuralgia lasts for more than 1 month after recovery; 3. Age >=18 years old; 4. Visual simulation score >=4 points; 5. Shingles on the neck, chest and waist; 6. Complete clinical data.
Exclusion criteria
Exclusion criteria: 1. Hepatic and renal insufficiency; 2. Abnormal coagulation function; 3. Fitted with cardiac pacemaker and spinal cord stimulator; 4. There are serious spinal deformity, disc herniation, etc. 5. Injection site infection; 6. Poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Central sensitization score;Seurm BDNF;PSQI score; | — |
Countries
China
Contacts
Public ContactYingying Lou
Ningbo Medical Centre Lihuili Hospital
Outcome results
None listed