Post stroke cognitive impairment
Conditions
Interventions
Sham group:Pseudoanode tDCS stimulation + cognitive rehabilitation training was given.
Control group:Routine rehabilitation is given.
tDCS group:Anode transcranial direct current stimulation (tDCS) stimulation + cognitive rehabilitation training were given.
Sponsors
Xuzhou Rehabilitation Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The diagnosis conforms to the diagnostic criteria for Post Stroke Cognitive Impairment (PSCI) as outlined in the 'Expert Consensus on Post Stroke Cognitive Impairment Management 2021' published by the Chinese Stroke Association and the Expert Committee on Post Stroke Cognitive Impairment Management in 2021,MoCA score= 6 points; 2.Age ranges from 40 to 75 years old, all underwent head CT and MRI examinations; 3.Having sufficient visual and auditory resolution to undergo neuropsychological testing and other assessments; 4.First onset within 6 months after stroke,tital signs are stable; 5.The subjects and/or guardians provide informed consent and sign a consent form, which has been approved by the Ethics Committee of Xuzhou Rehabilitation Hospital.
Exclusion criteria
Exclusion criteria: (1) Patients with a history of brain diseases other than cerebrovascular disease, such as brain trauma, progressive supranuclear palsy, epilepsy, chronic subdural hematoma, Huntington's disease, normal pressure hydrocephalus, brain infection, brain tumor or known brain structural abnormalities, etc. (2) Exclude cognitive impairment caused by neurodegenerative diseases, congenital and hereditary diseases such as Alzheimer's disease, Parkinson's disease, Lewy body dementia, etc. (3) Patients with cognitive impairment caused by liver, kidney, thyroid and other systemic diseases, anemia, malnutrition and other reasons are excluded. (4) Patients with impaired consciousness, severe neurological deficits, inability to take care of themselves, severe dementia, etc., who are unable to complete the scale test, were excluded. (5) Exclude a history of alcohol, drug abuse, or dependence within the past 2 years. (6) Exclusion of pseudodementia caused by various other causes. (7) Subjects who, in the opinion of the investigator, are unable to comply with the study procedures. (8) Intracranial metal implants, magnetic sheets, pacemakers, or skull defects; (9) Personal or family history of epilepsy, psychiatric history (including febrile seizures in infancy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Loewenstein Occupational Therapy Cognitive Assessment(LOTCA) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuroimaging indicators;Neurophysiological indicators;Montreal Cognitive Assessment Scale(MoCA) Score; | — |
Countries
China
Contacts
Public ContactYingli Bi
Xuzhou Rehabilitation Hospital
Outcome results
None listed