Stroke, spinal cord injury, Parkinson's disease and other neurological diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age: >=18 years old; 2. Stroke: The diagnosis of ischemic stroke and hemorrhagic stroke is based on relevant diagnostic criteria 3 in Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018 and Chinese Guidelines for the Diagnosis and Treatment of Cerebral Hemorrhage (2019), respectively. Spinal cord injury: injury due to trauma (including cauda equina injury) or non-traumatic spinal cord injury (vasogenic infection or tumor), diagnosed according to the 2011 Neurological grading criteria 4. Meets the diagnostic criterion 5 for MS in the 2017 revised McDonald Standard. Meet the diagnostic criteria for Parkinson's disease in 2016 edition of China 6. Other neurological diseases, such as brain trauma, brain tumor, etc., meet the corresponding diagnostic criteria 7. Vital signs stable, conscious, informed and consenting to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Those with severe auditory comprehension or cognitive impairment that affects their understanding of the research process or provides accurate feedback; 2. Patients with other major diseases such as malignant tumors, severe mental illness, bleeding disorders, endocrine diseases or systemic immune system diseases; 3. Concomitant other serious physical diseases that affect fatigue: such as severe heart disease, liver disease, chronic obstructive pulmonary disease or other major diseases that may affect the individual's fatigue; 4. Those who have metal objects such as pacemakers, stents, and dentures installed in the body 5. Patients with a history of drug abuse, hormone therapy, or alcohol abuse within the past 6 months; 6. Pregnant or women preparing for pregnancy; 7. Participants who are unwilling or unable to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue;Safety evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cognitive Function;Sleeping;Emotion;Motor function;Activity of daily living;Heart rate variation;Functional near infrared spectroscopy;Motor evoked potential;Quality of living; | — |
Countries
China
Contacts
The First Affiliated Hospital of Nanjing Medical University