chronic obstructive pulmonary disease
Conditions
Interventions
Conventional treatment group:Health education and guidance, drug treatment, home oxygen therapy, pursed-lip breathing)
Home non-invasive positive pressure ventilation:On the basis of the conventional group, home non-invasive positive pressure ventilation treatment was given.
The combined treatment group was given home-based pulmonary rehabilitation treatment :The combined treatment group was given home-based pulmonary rehabilitation treatment (diaphragmatic breathing exer
Sponsors
Fourth Hospital of Changsha City, Hunan Province.
Eligibility
Sex/Gender
All
Age
50 Years to 78 Years
Inclusion criteria
Inclusion criteria: Patients with stable stage severe (GOLD pulmonary function grade 3) chronic obstructive pulmonary disease (COPD) combined with arterial partial pressure of carbon dioxide (PaCO2) = 50 mmHg. The diagnosis of COPD in these patients conforms to the 2013 Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease by the Respiratory Society of the Chinese Medical Association. The age range is 50 to 75 years old. They have quit smoking and the disease course is 10 to 15 years. The 6-minute walking distance is more than 150 meters. They have agreed to this clinical trial and signed the informed consent form, and the experimental research has been approved by the hospital ethics committee.
Exclusion criteria
Exclusion criteria: (1) Those who do not cooperate with this study; (2) Combined with neurological diseases that affect muscle strength; (3) Combined with important organ dysfunction or lesions; (4) Combined with mental and neurological diseases and cognitive communication disorders; (5) Untreated pneumothorax; (6) There are other contraindications for pulmonary rehabilitation treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Medical Research Council (mMRC) score ;Pulmonary function FEV1 index;exercise endurance assessment - 6-minute walking distance (6MWT);body mass index (BMI);mean pulmonary artery pressure;arterial partial pressure of oxygen and carbon dioxid; | — |
Countries
China
Contacts
Public Contactyangfangying
Fourth Hospital of Changsha City, Hunan Province.
Outcome results
None listed