None
Conditions
Interventions
A:Induction was performed with a combination of 50 mg of phenobarbital and 20 mg of esketamine at a dose 0.15-0.2 ml/kg, and anesthesia was maintained with a continuous infusion of the combination at
B:Induction was performed with a combination of 50 mg of phenobarbital and 30 mg of esketamine at a dose 0.15-0.2 ml/kg, and anesthesia was maintained with a continuous infusion of the combination at
C:Induction was performed with a combination of 50 mg of phenobarbital and 40 mg of esketamine at a dose 0.15-0.2 ml/kg, and anesthesia was maintained with a continuous infusion of the combination at
Sponsors
Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital)
Eligibility
Sex/Gender
Female
Age
22 Years to 65 Years
Inclusion criteria
Inclusion criteria: The patient is a female aged 18-65 years, with a BMI of 18-30 kg/m^2, ASA class-III, undergoing hysteroscopy, and has signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1 Allergy or contraindication to the drugs related to this study; 2 Long-term use of opioid drugs; 3 Severe disease, respiratory disease, liver and kidney dysfunction, increased intracranial and intraocular pressure, history of hyperthyroidism; 4 Unable to provide on treatment effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory depression;Sedation score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate;the incidence of adeverse events;Pain score;Blood pressure;Pulse Oxygen Saturation;Mixture consumption; | — |
Countries
China
Contacts
Public ContactCongjie Bi
Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital)
Outcome results
None listed