Functional constipation
Conditions
Interventions
760 group:Bifidobacterium longum 760 powder
22m1 group:Bifidobacterium longum 22m1 powder
Sponsors
The Second Affiliated Hospital of Nanjing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Gender and race are not limited, and the age is 18 years old or above; 2. Must meet the diagnostic criteria of Rome IV. Functional constipation and exclude functional defecation disorders.
Exclusion criteria
Exclusion criteria: (1) Those who need to take other laxatives at the same time; (2) Patients who refused to sign the informed consent form, or who were estimated to have poor compliance and poor follow-up possibility; (3) Those who take probiotic products within 2 weeks; (4) Those who take antibiotics within 2 weeks; (5) Subjects who are considered by the investigator to be unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation Symptom Score ;Bristol Stool Characteristics Score;Gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient Assessment of Constipation Quality of Life questionnaire;Patient Assessment of Constipation Symptoms;Self-Rating Anxiety Scale ;Self-rating depression scale; | — |
Countries
China
Contacts
Public ContactHeiying Jin
The Second Affiliated Hospital of Nanjing University of Chinese Medicine
Outcome results
None listed