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Research on the Mechanism of Whole-Body Vibration Training in Regulating Corticospinal Tract-Motor Unit to Alleviate Joint-Derived Muscle Inhibition in Knee Osteoarthritis

Research on the Mechanism of Whole-Body Vibration Training in Regulating Corticospinal Tract-Motor Unit to Alleviate Joint-Derived Muscle Inhibition in Knee Osteoarthritis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096589
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-01-31
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis (KOA)

Interventions

Experimental group 1:Whole body vibration training 20 min + regular rehabilitation 30 min
60 degrees of knee flexion
Intervention 2-4 times per week for 8 weeks for a total of 24 sessions.
Experimental group 2:Whole body vibration training 20 min + regular rehabilitation 30 min
Bend the knee 60 degrees while placing an elastic band in the middle of the thigh and abducting the hip
Control group:Routine rehabilitation for 30min

Sponsors

Shanghai Yangzhi rehabilitation hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
38 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for knee osteoarthritis; 2. Aged between 38 and 80 years; 3. Classified as Grade II-III according to the Kellgren-Lawrence radiographic classification; 4. No knee-related medication or physical therapy within 1 month prior to enrollment; 5. Pain: Visual Analog Scale (VAS) score >=3; 6. No cognitive or communication impairments; 7. Provides signed informed consent;

Exclusion criteria

Exclusion criteria: 1. Osteoporosis; 2. Any other pathological conditions, such as congenital dysplasia, septic arthritis, or Baker's cyst; 3. Inability to participate in assessments or interventions due to comorbidities; 4. Unable to walk or walking distance less than 7.6 meters; 5. Exercise-induced or uncontrolled angina within the past 3 months; 6. Uncontrolled hypertension;

Design outcomes

Primary

MeasureTime frame
Maximal quadriceps strength.;

Secondary

MeasureTime frame
Pain(VAS);Knee joint mobility (ROM);Timed Up and Go (TUG) test;Knee Injury and Osteoarthritis Outcome Score (KOOS);6 Minute Walk Distance Test (6MWDT);Star Excursion Balance Test (SEBT);Quality of life;Motor evoked potentials and resting motor threshold;Surface EMG parameters (number of motor units, recruitment threshold, and discharge frequency);

Countries

China

Contacts

Public ContactFanjia Wang

Shanghai Yangzhi rehabilitation hospital

wangfanjiar@163.com+86 21 37730011

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026