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Clinical study of GnRH pulse therapy in the induction of ovulation in polycystic ovary syndrome

GnRH pulse pumps in ovulation induction in polycystic ovary syndrome - GnRH pulse pumps in ovulation induction in polycystic ovary syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096588
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-02-10
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic ovary syndrome

Interventions

1:The experimental group was treated with GnRH pulse pump
2:Rhe control group was treated with ovulation-promoting drugs (letrozole combined with HMG)

Sponsors

West China Second University hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1) Body mass index: 19 <= BMI <= 24 kg/m^2 2) Waist circumference less than or equal to 85cm 3) Diagnosed with polycystic ovary syndrome (PCOS). 4) Fertility requirement 5) Husband's semen is normal 6) No history of infertility or history of infertility with bilateral tubal patency on tubalography. 7) willing to participate in the clinical study

Exclusion criteria

Exclusion criteria: 1) Body mass index >24kg/m^2 2) Abdominal circumference >85cm 3) Allergic to adhesive tape, GnRH and its analogues. 4) No fertility requirements 5) Husband's semen abnormality can't conceive naturally. 6) Infertile patients with bilateral tubal adhesion or obstruction as shown by tubalography. 7) Combination of serious medical and surgical diseases or uterine malformations, gynaecological diseases that affect fertility. 8) Refusal to participate in the clinical study

Design outcomes

Primary

MeasureTime frame
Ovulation recovery rate;

Secondary

MeasureTime frame
Improvement in sex hormone levels;Pregnancy status (ultrasound indicators);

Countries

China

Contacts

Public ContactCheng Meng

West China Second University hospital of Sichuan University

ttt-cheng@163.com+86 138 8225 5774

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026