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Study on the effect of Shensong Yangxin capsule combined with dronedarone on maintaining sinus rhythm after radiofrequency ablation for persistent atrial fibrillation

Study on the effect of Shensong Yangxin capsule combined with dronedarone on maintaining sinus rhythm after radiofrequency ablation for persistent atrial fibrillation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096575
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-02-20
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

intervention group:The total course of treatment for Shensong Yangxin Capsules 1.6g tid+Dronedarone 400mg bid orally was 3 months, and later changed to Shensong Yangxin Capsules 1.6g tid to maintain f
control group:Dronedarone 400mg bid for a total course of 3 months

Sponsors

Mianyang 404 Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with persistent atrial fibrillation aged >= 18 years and <= 85 years old; 2. NYHA functional class I-III; 3. Perform radiofrequency ablation for atrial fibrillation. 4. Obtain informed consent from the patient and complete a 1-year follow-up.

Exclusion criteria

Exclusion criteria: 1. Unable to complete the expected 1-year follow-up; 2. Serious hematological disorders with contraindications to anticoagulation; 3. Left atrial diameter >= 65mm; 4. Left atrial appendage thrombus (transesophageal ultrasound examination); 5. NYHA functional class IV; 6. Hyperthyroidism or hypothyroidism; 7. Severe liver and kidney dysfunction; 8. Expected survival time<1 year; 9. Other arrhythmias/malignant arrhythmias

Design outcomes

Primary

MeasureTime frame
1-year recurrence rate of atrial fibrillation after radiofrequency ablation;complication;

Secondary

MeasureTime frame
Evaluation of quality of life;Decreased heart rate;

Countries

China

Contacts

Public ContactZhou Tao

Mianyang 404 Hospital

331762177@qq.com+86 135 6853 0770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026