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Clinical observation and fMRI brain imaging study on the mechanism of Yang Jizhou 's acupuncture treatment to postprandial distress syndrome after ischemic stroke

Clinical observation and fMRI brain imaging study on the mechanism of Yang Jizhou 's acupuncture treatment to postprandial distress syndrome after ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096560
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-06-01
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke postprandial distress syndrome

Interventions

Acupuncture groups:Acupuncture acupoints : Zhongfeng, Rangu, Neiting, Lidui, Yinbai, Yinlingquan, Feishu, Pishu, Weishu, Xiaochangshu
Drug group:Oral domperidone, 10 mg / time, 3 times / day
Healthy control group:None

Sponsors

Quzhou Municiple Hospital of Traditonal Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: ( 1 ) Conform to the diagnostic criteria of ischemic stroke and postprandial distress syndrome ; ( 2 ) 40 <= age <= 70 ; ( 3 ) Patients who did not receive treatment for postprandial distress syndrome within 2 weeks ; ( 4 ) Those who did not take drugs affecting gastrointestinal motility within 2 weeks ; ( 5 ) Physical examination cooperation, clear and fluent language, accurate expression, no cognitive and conscious disorders ; ( 6 ) High school degree or above ; ( 7 ) Right handedness ; ( 8 ) There was no metal implant in the body and no contraindication for nuclear magnetic resonance scanning. ( 9 ) Consciously participate in the experiment and sign the informed consent.

Exclusion criteria

Exclusion criteria: ( 1 ) combined with peptic ulcer, gastric mucosal hyperplasia or other organic lesions ; ( 2 ) Patients with severe anxiety and depression and suicidal tendency ; ( 3 ) Combined liver dysfunction (ALT and AST exceeding the upper limit of normal by 1.5 times) and renal dysfunction (Cr exceeding the upper limit of normal and BUN exceeding 1.2 times the upper limit of normal). ( 4 ) Combined with severe heart disease, cholecystitis, gallstones and metabolic system diseases ; ( 5 ) pregnant and lactating women ; ( 6 ) Female patients with severe dysmenorrhea, patients with obvious headache and migraine, patients with a history of head trauma ; ( 7 ) with severe depression, anxiety symptoms ; ( 8 ) patients with clear organic lesions or severe head anatomical structure asymmetry ;

Design outcomes

Primary

MeasureTime frame
Dyspepsia Symptom Score;Brain Functional Imaging;

Secondary

MeasureTime frame
Nepean Dyspepsia Symptom Index;Self-Rating Depression Scale;National Institute of Health stroke scale;

Countries

China

Contacts

Public ContactShao Wei

Quzhou Municiple Hospital of Traditonal Chinese Medicine

852272089@qq.com+86 131 5708 8250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026