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Effect of oxycodone preventive analgesia on postoperative recovery quality of patients at high risk of pain after upper digestive tract ESD surgery

Effect of oxycodone preventive analgesia on postoperative recovery quality of patients at high risk of pain after upper digestive tract ESD surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096557
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-02-05
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain of ESD

Interventions

Control group:Equal amounts of saline
Sufentanil group:Sufentanil was given 0.1µg/kg before anesthesia induction
Oxycodone group 1:0.1mg/kg oxycodone was given before induction of anesthesia
Oxycodone group 2:0.1mg/kg oxycodone was administered 30 minutes before the end of surgery

Sponsors

Liaocheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Upper gastrointestinal ESD patients with incidence of postoperative pain >= 20% with preoperative nomogram. 2. Age >=40 years older.

Exclusion criteria

Exclusion criteria: The operation time is more than 2 hours;Patients with severe respiratory and circulatory diseases, neurological diseases or mental and psychological disorders; patients with obvious liver and kidney dysfunction; patients with allergies to experimental drugs; patients taking drugs (including anti-tumor drugs and painkillers) for a long time; patients participating in other clinical trials, etc

Design outcomes

Primary

MeasureTime frame
The most severe VAS score within 24 hours after surgery;QOR- 15 score;

Secondary

MeasureTime frame
PPI score;SF-MPQ pain score;Time and dose of postoperative analgesic drugs;Ramsay score after extubation;PACU residence time;

Countries

China

Contacts

Public ContactShanshan Wu

Liaocheng People's Hospital

by09shan@163.com+86 182 6453 7605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026