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A comparative study on the changes of CGRP content between cyclopropofol and propofol during anesthesia induction in hypertensive patients

A comparative study on the changes of CGRP content between cyclopropofol and propofol during anesthesia induction in hypertensive patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096547
Enrollment
Unknown
Registered
2025-01-26
Start date
2025-01-27
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

Propofol group:General anesthesia was induced with propofol
Cyclopofol group:General anesthesia was induced with cyclopofol

Sponsors

The First People's Hospital of Linping District, Hangzhou
Lead Sponsor

Eligibility

Sex/Gender
All
Age
55 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Age: 55-75 years old; (2) American College of Anesthesiologists classification(ASA) Grade II patients; (3) Understand the content of this experiment and agree to sign the informed consent; (4) Patients undergoing general anesthesia surgery at an appropriate time; (5) According to the latest regulations of WHO in 2022, diagnosis criteria Hypertension was confirmed and blood pressure was controlled by regular medication at 110-150/70-100mmHg.There were no complications in the circumference.

Exclusion criteria

Exclusion criteria: 1) the patient or family refused to participate in the trial; 2) patients with poor preoperative blood pressure control; 3) patients with diabetes and other metabolic diseases; 4) patients with a history of cerebrovascular disease, cerebral infarction or neurological diseases such as epilepsy; 5) Allergic to cyclopropofol, components of propofol injection and other anesthetic drugs; 6) pregnant and lactating women; 7) use of psychotropic drugs.

Design outcomes

Primary

MeasureTime frame
Calcitonin gene-related peptide;Average blood pressure;

Secondary

MeasureTime frame
Pulse rate;Sedation index;Pain Threshold index;

Countries

China

Contacts

Public ContactZhang Ying

The First People's Hospital of Linping District, Hangzhou

237368558@qq.com+86 153 5502 8365

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026