Skin and soft tissue tumour
Conditions
Interventions
Experimental group:Mix sodium hyaluronate gel for injection and methylene blue for injection 1 to 1. The PI will use a 2 ml syringe and a 27G*14mm needle to inject into the dermis at the marked tumour
Control group:Conventional approach: depiction of tumour boundaries visible to the naked eye with a marker pen.
Sponsors
The First Medical Center of Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Patients with malignant tumours of the soft tissues of the skin, with the type of tumour including but not limited to, basal cell carcinoma, squamous cell carcinoma, malignant melanoma, fibrosarcoma, liposarcoma, and hemangiosarcoma, attending the First Medical Center of the Chinese PLA General Hospital; (2) The patient is at least 18 years old; (3) There are biopsy pathology results for clear diagnosis; (4) There are indications for surgery; (5) Patients who agree to participate and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients who do not have indications for surgery; (2) Patients who are under 18 years old, pregnant or breastfeeding; (3) Allergic to hyaluronic acid or methylene blue; (4) Infection at the proposed injection site; (5) Patients who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distance between the tumor's pathological border and the edge of the surgical incision, and the area of healthy tissue between them;Repair Modality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications;Cost;Surgical Time;Postoperative Patient-Reported Outcome Scores(FACE-Q); | — |
Countries
China
Contacts
Public ContactYoubai Chen
No.28, Fuxing Road, Haidian District, Beijing City
Outcome results
None listed