Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Conditions
Interventions
Oliceridine group:Oliceridine for Intraoperative Analgesia
Fentanil group:fentanil for Intraoperative Analgesia
Sponsors
Changshu Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients with ASA grade I-III; 2. Patients aged 18-85 years; 3. Patients with Body mass index (BMI) : 18-30?/m2;
Exclusion criteria
Exclusion criteria: 1. Patients with severe organ dysfunction such as heart, lung, liver, kidney and brain before operation; 2. Patients with adrenal disease, diabetes and other endocrine diseases; 3. Patients with a history of abuse or long-term use of narcotic sedative or analgesic drugs, or drug or alcohol abuse; 4. Patients with mental or neurological diseases or dysfunction; 5. Patients with a history of severe hypertension or hypotension;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative Nausea and Vomiting Incidence and Frequency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemodynamics Before and After Anesthesia Induction, Before and After Extubation, and in the PACU;Anesthesia Recovery Time, Anesthetic Drug Dosage, and Vasopressor Dosage;Postoperative VAS Pain Scores, Rescue Analgesic Rate, Pittsburgh Sleep Quality, Patient Satisfaction, and Other Adverse Reactions; | — |
Countries
China
Contacts
Public ContactXu Fangsheng
Changshu NO.2 people's Hospital
Outcome results
None listed