breast cancer
Conditions
Interventions
Experiment group:Continuous pumping of esketamine 0.3 mg/kg/h
Control group:Pump an equal amount of physiological saline
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: In the First Affiliated Hospital of Chongqing Medical University, patients aged 18-65 years old, with a BMI of 18.5-30kg/m2 and an American Association of Anesthesiologists (ASA) rating of I-II, who were selected to undergo modified radical surgery for breast cancer under general anesthesia, signed informed consent.
Exclusion criteria
Exclusion criteria: Patients with severe pulmonary hypertension, arrhythmia, liver and kidney dysfunction, uncontrolled hypertension, recent use of analgesics, long-term use of sleeping pills, history of chronic pain, pregnancy, lactation, history of alcohol and/or drug abuse, severe sensory organ defects (such as visual or hearing impairment) or inability to communicate normally, comorbid mental illness, and refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ISI scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep time ;Extubation time;The incidence of complications after extubation;Hospital stay;VAS score;Remedial analgesia within 48hours after surgery;Postoperative adverse reactions;PSQI score;HADS score;Vital signs;Anesthetic dosage; | — |
Countries
China
Contacts
Public ContactKaihua He
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed