Atrophic vaginitis(AV)
Conditions
Interventions
CO2 laser group:The Smart Xide2 C60 CO2 Fractional Laser manufactured by DEKAM. E. L. A. Srl (Italy) was used for 360° treatment of the vaginal wall with a disposable laser cannula, with an output pow
Sponsors
The Second Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Spontaneous amenorrhea for 12 months; Six weeks after bilateral oophorectomy, with or without hysterectomy; Spontaneous amenorrhea for 6 months, with serum FSH > 40 mIU/mL. In postmenopausal women who meet the above criteria, those who experience symptoms such as vulvovaginal burning, dryness, and dyspareunia, and for whom estrogen therapy is contraindicated or should be used with caution due to personal medical reasons, are candidates for fractional laser therapy.
Exclusion criteria
Exclusion criteria: 1. Laser allergy; 2. History of vulvar or vaginal surgery; 3. Other vulvar or vaginal diseases; 4.Currently using vaginal hormone therapy or vaginal moisturizers; 5. Undiagnosed vaginal bleeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal Health Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| vaginal microbiota composition;female sexual function index;IL1ß,IL6,IL10,IL8; | — |
Countries
China
Contacts
Public ContactLedan Wang
The Second Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed