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Clinical research and mechanism exploration on the difference in efficacy of preoperative drug therapy and changes in surgical difficulty in patients with renal cell carcinoma and inferior vena cava tumor thrombus

Clinical research and mechanism exploration on the difference in efficacy of preoperative drug therapy and changes in surgical difficulty in patients with renal cell carcinoma and inferior vena cava tumor thrombus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096502
Enrollment
Unknown
Registered
2025-01-24
Start date
2025-02-05
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal tumor with venous tumor thrombus

Interventions

Case series:None

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Renal tumor patients with inferior vena cava tumor thrombus who received preoperative drug treatment and are scheduled for surgical treatment at our hospital; (2) Patients aged between 18 and 75 years.

Exclusion criteria

Exclusion criteria: (1) Preoperative drug treatment duration less than 1 month; (2) Irregular preoperative drug treatment; (3) Previous treatments other than drug therapy prior to surgery; (4) History of surgery on the affected kidney; (5) Abdominal surgery history resulting in intra-abdominal adhesions; (6) Congenital or acquired solitary kidney; (7) Coexisting malignant tumors in other systems.

Design outcomes

Primary

MeasureTime frame
Preoperative drug treatment data;Imaging examination data;Intraoperative fat adhesion degree;Renal tumor and inferior vena cava tumor thrombus data;

Secondary

MeasureTime frame
Demographic information;Comorbidities;Liver function;Kidney function;Surgical methods;Operation time;Intraoperative blood loss;Intraoperative blood transfusion;Pathology type;Pathology staging and grading;Survival data;Postoperative complications;

Countries

China

Contacts

Public ContactQingbo Huang

Chinese PLA General Hospital

gdhuangqingbo@163.com+86 139 0427 5683

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026