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A study on the relationship between serum vitamin D levels and the risk of irAEs in patients receiving PD-1 drug treatment

A Study on the Relationship Between Serum Vitamin D Levels and the Risk of IrAEs in Patients Receiving PD-1 Therapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096501
Enrollment
Unknown
Registered
2025-01-24
Start date
2025-02-17
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oncology diabetes

Interventions

PD-1 treatment group:None

Sponsors

Changxing County People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Chemotherapy patients diagnosed with malignant tumors through pathology; 2.Age >= 18 years old; 3.Patients who are eligible for single drug therapy and/or combination therapy with anti PD-1 inhibitors; 4.No previous history of inflammation or severe autoimmune diseases in the same affected organs;

Exclusion criteria

Exclusion criteria: 1.There are clear serious heart and lung diseases, autoimmune diseases, and immunodeficiency diseases; 2.Severe illness or death during hospitalization; 3.Non PD-1/PD-L1 monotherapy and/or combination therapy; 4.Have a history of taking vitamin D and related products, calcium supplements, and hormones orally in the past 6 months;

Design outcomes

Primary

MeasureTime frame
Occurrence of adverse reactions;

Countries

China

Contacts

Public ContactYue Zhang

Changxing County People's Hospital

997842346@qq.com+86 18205825756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026