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Application Research on Intraoperative Lung Protective Ventilation Strategies Guided by Electrical Impedance Tomography in Laparoscopic Surgery

Application Research on Intraoperative Lung Protective Ventilation Strategies Guided by Electrical Impedance Tomography in Laparoscopic Surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096498
Enrollment
Unknown
Registered
2025-01-24
Start date
2025-02-11
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative atelectasis

Interventions

Conventional lung protective ventilation group (Group C):Conventional lung-protective ventilation strategies.
Intraoperative lung protective ventilation strategy guided by electrical impedance tomography (Group E):Intraoperative lung protective ventilation strategy guided by electrical impedance tomography

Sponsors

Xuanwu Hospital Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
60 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing gynecological laparoscopic surgery under general anesthesia; 2. Age >= 60 years old; 3. Duration of intraoperative laparoscopic pneumoperitoneum >= 1h; 4. ASA grade I-III, NYHA grade I-II.

Exclusion criteria

Exclusion criteria: 1.Patients with pre-existing pulmonary complications before surgery; 2.Patients with preoperative cardiac insufficiency; 3.Patients who are unable to undergo intraoperative electrical impedance tomography (EIT) monitoring due to other reasons (including those using pacemakers, implantable cardioverter defibrillators, and other electronically active implants, etc.); 4.Patients who are transferred to the intensive care unit (ICU) after surgery unplanned;

Design outcomes

Primary

MeasureTime frame
The incidence of atelectasis after surgery;—

Secondary

MeasureTime frame
Cardiac function was evaluated 1 hour after operation;Intraoperative respiratory mechanics (plateau pressure, peak airway pressure, mean airway pressure, lung compliance, mechanical power);Intraoperative EIT parameters (ROI%, RVD, COV, GI);Incidence of hypoxemia at 1 hour after surgery;Lung ultrasound score at 1 hour after surgery;Intraoperative hemodynamic parameters (MAP, HR);Intraoperative blood gas analysis;Incidence of PPCs 7 days after surgery;Simplified clinical pulmonary infection score,sCPIS;Serum inflammatory factors: IL-6, TNF-a, hs-CRP;—

Countries

China

Contacts

Public ContactTianlong Wang

Xuanwu Hospital Capital Medical University

w_tl5595@hotmail.com+86 10 83199333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026