Anxiety, stress, sleep disorders
Conditions
Interventions
VB1&VB2 group:Vitamin B1 and vitamin B2 health supplement tablets each contain 100mg of vitamin B1 or vitamin B2
Placebo group:The placebo group received two sucrose tablets with the same appearance, smell, color, taste, and packaging as the vitamin B1 and vitamin B2 supplements.
Sponsors
Macau University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Interested participants were first screened on-site and required to meet the following inclusion criteria: 1) age 18-25 years; 2) Self-Rating Anxiety Scale (SAS) score of at least 50; 3) Perceived Stress Scale (PSS) score at least 13; 4) Pittsburgh Sleep Quality Index (PSQI) score of at least 6; 5) score at least 6 on the Epworth Sleepiness Scale (Epworth Sleepiness Scale).
Exclusion criteria
Exclusion criteria: Individuals with 1) BMI less than 18.5 and more than 40 kg/m^2 were excluded from this study; 2) the content of vitamin B1 in urine is more than 200ug, and the content of vitamin B2 in urine is more than 800ug; 3) individuals experiencing stress such as bankruptcy, love failure, and a history of death within the past six months in first-degree relatives and close friends. 4) with neurological or organic diseases; 5) pathological anxiety (e.g., generalized anxiety disorder (GAD)) or psychiatric disorders (e.g., post-traumatic stress disorder); Individuals diagnosed with inflammatory diseases and other specific diseases such as diabetes, cardiovascular disease, cancer, hypertension, renal disease, liver disease, hyperthyroidism, epilepsy, and MS. 6) diagnosed with a pathologic sleep disorder (e.g., severe insomnia, severe obstructive sleep apnea syndrome); 7) recent history of alcohol or drug use (past 3 months); 8) pregnant or lactating women. In addition, subjects who failed to complete the questionnaire and correctly followed the instructions were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitamin B1 and vitamin B2 nutritional levels;Anxiety scale score;Stress scale score;Sleep QUALITY SCORE; | — |
Countries
China
Contacts
Public ContactXi Yu
Macao University of Science and Technology
Outcome results
None listed