gynecology department
Conditions
Interventions
Control group:Use of opioids
LOA group:Use esketamine and dexmedetomidine in combination with sufentanil
Sponsors
The First People's Hospital Lianyungang
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective endoscopic gynecological surgery. 2. American Association of Anesthesiologists (ASA) Patient Grade I to II. 3. Age 20-60 years old. 4. Patients were informed of the main test methods and possible adverse reactions, and signed informed consent. 5. Heart, lung, liver, kidney and coagulation function were not abnormal. 6. The patient requested the use of a self-controlled analgesic device after surgery.
Exclusion criteria
Exclusion criteria: 1, ASA? level or above; 2. A history of allergy to or contraindication to ropivacaine, esketamine, or nonsteroidal anti-inflammatory drugs (NSAID) (serious risk of elevated blood pressure and intracranial pressure, poorly controlled or untreated hypertension, untreated or undertreated hyperthyroidism, gastrointestinal bleeding); 3, have mental illness and other chronic pain or other conditions that may confuse the analgesic response; 4, can not read and write Chinese, communication barriers; 5. Patients with severe heart disease and respiratory disease; 6. Patients with serious skin damage and infection in the ultrasound scan area; 7. Reluctance to use intravenous pain relief pumps and refusal to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quality of Recovery-40; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale (VAS) scores;heart rate ;Use of sufentanil;The number of effective compressions of the analgesic pump;Incidence of bradycardia;Incidence of nausea and vomiting;Incidence of dizziness;Incidence of increased oral secretions;Incidence of respiratory depression; | — |
Countries
China
Contacts
Public ContactHao Conghui
The First People's Hospital Lianyungang
Outcome results
None listed