inguinal hernia
Conditions
Interventions
group S1(0.1mg/kg esketamine):Intravenous injection 0.1mg/kg esketamine
group S2(0.2mg/kg esketamine):Intravenous injection 0.2mg/kg esketamine
Group C (normal saline 0.1ml/kg):Intravenous injection of 0.1ml/kg normal saline
Sponsors
Children's Hospital,Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.laparoscopic inguinal hernia repair under general anesthesia; 2.aged 24~71 months; 3.American Society of Anesthesiologists Physical Status I or II; 4.body mass index for age between the 5th and 85th percentiles;
Exclusion criteria
Exclusion criteria: 1.allergy to esketamine; 2.abnormal liver or kidney function; 3.glaucoma or neurological disorders; 4.cardiovascular or endocrine dysfunction; 5.asthma or respiratory infection in the last 2 weeks; 6.developmental delay;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of emergence delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence of postoperative pain;Tracheal catheter extubation time;The time of emergence from anesthesia;Recovery time;The incidence of adverse effects;Blood pressure and heart rate; | — |
Countries
China
Contacts
Public Contactjinpengqiu
Children's Hospital,Zhejiang University School of Medicine
Outcome results
None listed