Lung cancer
Conditions
Interventions
None:None
Sponsors
Shandong University of Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 years old 2. All patients were treated for the first time and confirmed as lung adenocarcinoma by postoperative histopathology 3. The postoperative tumor staging of all patients was classified as stage?-? 4. All subjects showed no abnormalities in vital signs, electrocardiogram and laboratory tests 5. No clear history of the central nervous system, cardiovascular system, kidney, liver, digestive tract, respiratory system, metabolism, or musculoskeletal system 6. Informed consent of the person or authorized client 7. Did not participate in any other study 8. Regular follow-up can be performed
Exclusion criteria
Exclusion criteria: 1. Previous history of other malignant tumors 2. Positive surgical margin 3. Had received any anti-tumor treatment such as radiotherapy, chemotherapy, immunotherapy and preoperative neoadjuvant therapy before surgery 4. Clinical evidence of any infectious inflammatory condition such as fever and chills within 1 month before surgery 5. Use of any drugs that may affect the results of hematological examination within 1 month before surgery 6. Preoperative complications such as liver disease, blood system disease or severe organ failure 7. Any other clinically significant disease or condition that was considered by the investigator to be likely to affect adherence to the protocol or to affect informed consent or to preclude participation in the study If the answer was "yes" to any of the above, they could not enter the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multi-immune site studies of regulatory T cells and others in the immune microenvironment;Single-cell RNA sequencing (scRNA-seq) of surgically resected tumour tissues from 30 postoperative patients with lung adenocarcinoma and gene expression profiling of cancer cells and immunity to fine at the single-cell level; | — |
Countries
China
Contacts
Public ContactZhang Jingshun
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Outcome results
None listed