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Clinical efficacy and adverse reaction monitoring of all trans retinoic acid tablets in patients with genital warts in the vagina, urethral opening, perianal and anal canal

Clinical efficacy and adverse reaction monitoring of all trans retinoic acid tablets in patients with genital warts in the vagina, urethral opening, perianal and anal canal

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500096465
Enrollment
Unknown
Registered
2025-01-24
Start date
2025-02-05
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condyloma acuminatum

Interventions

Retinoic acid group:Oral administration of (all trans) tretinoin tablets (10mg po tid) for 2 weeks, followed by electrocautery at the rash site and subcutaneous injection of interleukin-2 (1 million u

Sponsors

The Second Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old 2. Condyloma acuminatum was diagnosed as primary and no reinfection, no other sexually transmitted diseases, no immunosuppressive constitution (such as autoimmune diseases, diabetes, tumors, transplantation, history of long-term use of antibiotics, glucocorticoids, immunosuppressants, biological agents, JAK inhibitors, chemotherapy drugs, targeted drugs and other medical history), and no other drugs were used during the treatment period; Patients who have no history of using antiviral or anti-tumor drugs before treatment and agree to use (all trans) retinoic acid tablets. 3. No history of allergy to (all trans) retinoic acid tablets or contraindications to the use of (all trans) retinoic acid tablets. 4. Agree to participate in the follow-up and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with other serious complications that may affect the assessment or treatment of their condition. 2. Individuals with mental illnesses; Those who cannot insist on re examination. Patients who are unable to use strict contraception during treatment and those who are unable to use strict contraception after stopping medication for one year. Recent exposure to sunlight and long-term alcohol consumption cannot avoid drinkers.

Design outcomes

Primary

MeasureTime frame
Therapeutic effect on warts;

Secondary

MeasureTime frame
Adverse reactions;

Countries

China

Contacts

Public ContactLulu Tang

The Second Affiliated Hospital of Guangxi Medical University

tanglulu1@yeah.net+86 180 7654 4349

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026