Genitourinary Syndrome of Menopaus (GSM)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.(Conforming to any of the following): The age of women >=40 years, and FSH>40U/L, after hysterectomy; The age of women >=40 years, and menopause >=12 months;The age of women >=20 and <=40 years,and no GSM symptoms; 2.Women have at least one of the following symptoms. (1) Reproductive tract related symptoms: itching of the vulva or vagina, vaginal dryness, burning pain, repeated abnormal discharge, etc.; (2) Urinary tract related symptoms: frequent urination, urgency, urethral discomfort, increased nocturia, dysuria, repeated urinary tract infections, etc.; (3) Changes in the quality of sexual life: decreased libido, dyspareunia, painful intercourse, etc.
Exclusion criteria
Exclusion criteria: 1. Acute inflammation of the reproductive tract; 2. Using hormone drugs in the past 3 months; 3. Using antibiotics or receiving GSM treatment in the past few months; 4. There are organic lesions such as skin lesions of the vulva, vaginal and cervical intraepithelial neoplasia, urinary tract tumors and stones; 5. In the past 1 month, vaginal drugs and preparations such as moisturizers and lubricants have been used; 6. Suffering from mental system diseases and organic encephalopathy; 7. Combined with chronic diseases affecting treatment compliance; 8. Patients who are participating in other clinical trials; 9. In the past 1 month, there have been cases of vaginal irrigation and other changes in the vaginal microenvironment; 10.Other reasons deemed unsuitable for clinical trials by the investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary tract microbiota differences;Vaginal microbiota differences; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Chongqing Medical University