Osteoporosis
Conditions
Interventions
Observation group:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
Female
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Postmenopausal women (at least 12 consecutive months without menstruation) or individuals aged 50 and above. 2.Individuals capable of undergoing ankle QCT and lumbar spine QCT, DXA scans, ensuring data comparability. 3.Voluntary participation in the study and signing of the informed consent form. 4.Patients eligible for laboratory tests (including liver, kidney, and blood function tests, blood calcium, blood phosphorus, alkaline phosphatase (ALP), parathyroid hormone (PTH), erythrocyte sedimentation rate (ESR), 25-hydroxyvitamin D, routine blood and urine tests, ß-collagen degradation products (ß-CTX), osteocalcin, serum creatinine, and cystatin C).
Exclusion criteria
Exclusion criteria: 1.Patients who have received osteoporosis treatment (such as bisphosphonates, estrogen, etc.) in the past two years and have continued treatment for more than 3 months. 2.Participants who cannot undergo stable scanning due to severe trauma or bone tumors in the spine or both feet. 3.Participants with a history of foot developmental abnormalities, severe trauma, or deformities that affect the normal structure of the ankle joint. 4.Participants with severe endocrine diseases (such as hyperparathyroidism) or those who have been on long-term medication affecting bone metabolism (such as hormonal drugs or anti-osteoporosis medications).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ankle QCT bone mineral density;Lumbar spine QCT bone mineral density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactWang Lei
Shanghai Sixth People's Hospital
Outcome results
None listed