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The Relationship between Perioperative Triglyceride-Glucose Index and Postoperative Delirium in Elderly Patients Undergoing Elective Non-Cardiac Surgery: A Prospective Cohort Study

The Relationship between Perioperative Triglyceride-Glucose Index and Postoperative Delirium in Elderly Patients Undergoing Elective Non-Cardiac Surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096339
Enrollment
Unknown
Registered
2025-01-22
Start date
2025-02-01
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Higher TyG index group:NA
Lower TyG index group:NA

Sponsors

The First Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: Planned elective non-cardiac surgery under general anesthesia, involving patients aged 65 and above, with an American Society of Anesthesiologists (ASA) classification of I to III, and an anticipated postoperative hospitalization duration of at least 3 days.

Exclusion criteria

Exclusion criteria: (1) Patients who lack the data required for the calculation of the perioperative triglyceride-glucose index; (2) Patients with a history of neurological and psychiatric disorders caused by dementia, delirium, or other etiologies; (3) Preoperative assessment of patients with cognitive dysfunction; (4) Patients admitted to the ICU postoperatively; (5) Patients scheduled for a second surgery within 7 days following their initial surgery; (6) Patients with a history of alcohol or drug dependency; (7) Patients who are currently using sedative or antidepressant medications, or who have recently used drugs that cross the blood-brain barrier; (8) Patients who are unwilling to cooperate with the investigation or are unable to do so due to communication difficulties, severe hearing or visual impairments.

Design outcomes

Primary

MeasureTime frame
Postoperative Delirium;

Secondary

MeasureTime frame
Incidence of delirium during postoperative recovery period;Postoperative pain score;Total length of hospital stay;Postoperative hospitalization time;30 days postoperative cognitive function;30 day all-cause mortality rate;

Countries

China

Contacts

Public ContactFang Bo

Department of Anesthesiology, The First Affiliated Hospital of China Medical University

bfang@cmu.edu.cn+86 135 9165 2719

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026