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Inflammatory biomarkers (neutrophil to albumin ratio NPAR; The ratio of platelet to lymphocyte (PLR); C-reactive protein, albumin and lymphocyte index CALLY to predict the clinical prognosis of children with sepsis and septic shock

Inflammatory biomarkers (neutrophil to albumin ratio NPAR; The ratio of platelet to lymphocyte (PLR); C-reactive protein, albumin and lymphocyte index CALLY to predict the clinical prognosis of children with sepsis and septic shock

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500096331
Enrollment
Unknown
Registered
2025-01-22
Start date
2025-01-25
Completion date
Unknown
Last updated
2025-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Case series:NA

Sponsors

West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: In this study, at least 2 points of the new Phoenix Sepsis Score (PSS) (including respiratory, cardiovascular, coagulation, and nervous system dysfunction) were used to determine whether children with suspected infections [<18 years old (excluding perinatal hospitalized newborns and premature infants (<37 weeks)] have sepsis. Septic shock is defined as sepsis with a PSS cardiovascular score of at least 1.

Exclusion criteria

Exclusion criteria: Several exclusion criteria were used, including patients over 18 years of age, patients with chronic kidney disease (CKD), patients with cirrhosis of the liver, and patients with an ICU stay of less than 24 hours.

Design outcomes

Primary

MeasureTime frame
neutrophil percentage–to–albumin ratio;C-reactive protein–albumin–lymphocyte index;platelet–to–lymphocyte ratio;Area under ROC curve;

Countries

China

Contacts

Public ContactChen Siyuan

West China hospital of Sichuan University

siy_chen@163.com+86 189 8060 6870

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026